Cell-instructive and stimuli-responsive injectable alginate hydrogels
نویسندگان
چکیده
منابع مشابه
Injectable alginate hydrogels for cell delivery in tissue engineering.
Alginate hydrogels are extremely versatile and adaptable biomaterials, with great potential for use in biomedical applications. Their extracellular matrix-like features have been key factors for their choice as vehicles for cell delivery strategies aimed at tissue regeneration. A variety of strategies to decorate them with biofunctional moieties and to modulate their biophysical properties have...
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UNLABELLED Mesenchymal stem cell (MSC)-based therapies are under broad investigation for applications in tissue repair but suffer from poor cell persistence and engraftment upon transplantation. MSC spheroids exhibit improved survival, anti-inflammatory, and angiogenic potential in vitro, while also promoting vascularization when implanted in vivo. However, these benefits are lost once cells en...
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There has been increasing interest in integrated microfluidic systems because performing biological and chemical laboratory tasks on a single chip is appealing. One straightforward approach to constructing these ‘lab on chips’ is to fabricate individual components and to assemble them for desired functionalities. As the functionalities of the microfluidic systems become increasingly complicated...
متن کاملStimuli-Responsive Hydrogels and Their Application to Functional Materials
Many kinds of stimuli-responsive polymer gels that respond to the change in their surroundings such as solvent composition, temperature, pH, and supply of electric field have been developed. They are of interest as intelligent (or smart, biomimetic) materials which have sensor, processor, and actuator functions. This article is related to stimuliresponsive gels and their application for bioor b...
متن کامل3D Cell Culture in Alginate Hydrogels
This review compiles information regarding the use of alginate, and in particular alginate hydrogels, in culturing cells in 3D. Knowledge of alginate chemical structure and functionality are shown to be important parameters in design of alginate-based matrices for cell culture. Gel elasticity as well as hydrogel stability can be impacted by the type of alginate used, its concentration, the choi...
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ژورنال
عنوان ژورنال: Frontiers in Bioengineering and Biotechnology
سال: 2016
ISSN: 2296-4185
DOI: 10.3389/conf.fbioe.2016.01.00161